Posts Tagged ‘immune-system’

Loosely coiled DNA helps trypanosomes make their escape

January 8th, 2010

Some animals use camouflage to outsmart their prey; others use mimicry or fake their own death. But Trypanosoma brucei, the wily parasite that causes African sleeping sickness, is the only organism we know of that can change its molecular identity on command to escape the grip of the human immune system. New research reveals a key discovery that has eluded scientists for decades: To avoid capture, trypanosomes must strategically uncoil their DNA.

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Loosely coiled DNA helps trypanosomes make their escape

Scientists identify DNA that regulates antibody production

November 19th, 2009

When foreign invaders trip the immune system’s alarm, antibodies need to be specially sculpted to attack them head on. New research now shows that gene segments called enhancers control the reshuffling of antibody genes that makes such a precise and coordinated attack possible.

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Scientists identify DNA that regulates antibody production

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